Publications

Below is a collection of many recent publications produced by or in partnership with the Singer Group.

Frailty and Body Composition:

Singer JP, Peterson ER, Snyder ME, et al. Body composition and mortality after adult lung transplantation in the United States. Am J Respir Crit Care Med. Nov 1 2014;190(9):1012-21. doi:10.1164/rccm.201405-0973OC

Singer JP, Diamond JM, Gries C, et al. Frailty phenotypies, disability, and outcomes in adult candidates for lung transplantation. Am J Respir Crit Care Med. 2015;192(11):1325-34. doi:10.1164/rccm.201506-1150OC

Singer JP, Lederer DJ, Baldwin MR. Frailty in Pulmonary and Critical Care Medicine. Ann Am Thorac Soc. Aug 2016;13(8):1394-1404. doi:10.1513/AnnalsATS.201512-833FR

Singer JP, Diamond JM, Anderson MR, et al. Frailty phenotypes and mortality after lung transplantation: A prospective cohort study. Am J Transplant. Aug 2018;18(8):1995-2004. doi:10.1111/ajt.14873

Singer JP, Soong A, Bruun A, et al. A mobile health technology enabled home-based intervention to treat frailty in adult lung transplant candidates: A pilot study. Clinical transplantation. Jun 2018;32(6):e13274. doi:10.1111/ctr.13274

Anderson MR, Kolaitis NA, Gao Y, et al. A nonlinear relationship between visceral adipose tissue and frailty in adult lung transplant candidates. Am J Transplant. Jul 6 2019;doi:10.1111/ajt.15525

Anderson MR, Udupa JK, Edwin E, et al. Adipose tissue quantification and primary graft dysfunction after lung transplantation: The Lung Transplant Body Composition study. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. Dec 2019;38(12):1246-1256. doi:10.1016/j.healun.2019.08.013

Courtwright AM, Zaleski D, Tevald M, et al. Discharge frailty following lung transplantation. Clinical transplantation. Oct 2019;33(10):e13694. doi:10.1111/ctr.13694

Venado A, McCulloch C, Greenland JR, et al. Frailty trajectories in adult lung transplantation: A cohort study. The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. Jul 2019;38(7):699-707. doi:10.1016/j.healun.2019.03.006

Anderson MR, Easthausen I, Gallagher G, et al. Skeletal muscle adiposity and outcomes in candidates for lung transplantation: a lung transplant body composition cohort study. Thorax. Jun 1 2020;doi:10.1136/thoraxjnl-2019-214461

Koons B, Greenland JR, Diamond JM, Singer JP. Pathobiology of frailty in lung disease. Translational research : the journal of laboratory and clinical medicine. Jul 2020;221:1-22. doi:10.1016/j.trsl.2020.04.001

Lai JC, Dodge JL, McCulloch CE, Covinsky KE, Singer JP. Frailty and the Burden of Concurrent and Incident Disability in Patients With Cirrhosis: A Prospective Cohort Study. Hepatol Commun. Jan 2020;4(1):126-133. doi:10.1002/hep4.1444

Perez AA, Hays SR, Soong A, et al. Improvements in frailty contribute to substantial improvements in quality of life after lung transplantation in patients with cystic fibrosis. Pediatr Pulmonol. Jun 2020;55(6):1406-1413. doi:10.1002/ppul.24747

Schaenman JM, Diamond JM, Greenland JR, et al. Frailty and aging-associated syndromes in lung transplant candidates and recipients. Am J Transplant. Dec 9 2020;doi:10.1111/ajt.16439

Venado A, Kolaitis NA, Huang CY, et al. Frailty after lung transplantation is associated with impaired health-related quality of life and mortality. Thorax. May 6 2020;doi:10.1136/thoraxjnl-2019-213988

Diamond JM, Courtwright AM, Balar P, et al. Mobile health technology to improve emergent frailty after lung transplantation. Clinical transplantation. Feb 2 2021:e14236. doi:10.1111/ctr.14236

Maheshwari JA, Kolaitis NA, Anderson MR, et al. Construct and Predictive Validity of Sarcopenia in Lung Transplant Candidates. Ann Am Thorac Soc. Feb 10 2021;doi:10.1513/AnnalsATS.202007-796OC

Anderson MR, Aronson KI, Diamond JM, Christie JD, Singer JP. Current Beliefs and Practices Regarding the Management of Obesity in Patients with Progressive Interstitial Lung Disease. Ann Am Thorac Soc. Apr 15 2022;doi:10.1513/AnnalsATS.202201-019RL

Hu A, Prosper A, Ruchalski K, et al. Sarcopenia Predicts Outcomes After Lung Transplantation in Older Lung Transplant Candidates. Annals of Thoracic Surgery Short Reports. 2022/11/09/ 2022;doi:https://doi.org/10.1016/j.atssr.2022.11.005

Singer JP, Calfee CS, Delucchi K, et al. Subphenotypes of frailty in lung transplant candidates. Am J Transplant. Apr 2023;23(4):531-539. doi:10.1016/j.ajt.2023.01.020

Singer JP, Christie JD, Diamond JM, et al. Development of the Lung Transplant Frailty Scale (LT-FS). The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. Feb 20 2023;doi:10.1016/j.healun.2023.02.006

Singer JP, Gao Y, Huang CY, et al. The Association Between Frailty and Chronic Lung Allograft Dysfunction After Lung Transplantation. Transplantation. 2023 Jun 8. doi: 10.1097/TP.0000000000004672

HRQL and Other Patient Centered Outcomes:

Perez AA, Hays SR, Soong A, et al. Improvements in frailty contribute to substantial improvements in quality of life after lung transplantation in patients with cystic fibrosis. Pediatr Pulmonol. Jun 2020;55(6):1406-1413. doi:10.1002/ppul.24747

Venado A, Kolaitis NA, Huang CY, et al. Frailty after lung transplantation is associated with impaired health-related quality of life and mortality. Thorax. May 6 2020;doi:10.1136/thoraxjnl-2019-213988

Singer JP, Yusen RD. Defining patient-reported outcomes in chronic obstructive pulmonary disease: the patient-centered experience. The Medical clinics of North America. Jul 2012;96(4):767-87. doi:10.1016/j.mcna.2012.05.005

Singer JP, Chen J, Blanc PD, Leard LE, Kukreja J, Chen H. A thematic analysis of quality of life in lung transplant: the existing evidence and implications for future directions. Am J Transplant. Apr 2013;13(4):839-50. doi:10.1111/ajt.12174

Singer JP, Katz PP, Iribarren C, et al. Both pulmonary and extra-pulmonary factors predict the development of disability in chronic obstructive pulmonary disease. Respiration; international review of thoracic diseases. 2013;85(5):375-83. doi:10.1159/000338110

Singer JP, Singer LG. Quality of life in lung transplantation. Seminars in respiratory and critical care medicine. Jun 2013;34(3):421-30. doi:10.1055/s-0033-1348470

Singer JP, Chen J, Katz PP, Blanc PD, Kagawa-Singer M, Stewart AL. Defining novel health-related quality of life domains in lung transplantation: a qualitative analysis. Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation. Dec 4 2014;doi:10.1007/s11136-014-0875-5

Singer JP, Chen J, Katz PP, Blanc PD, Kagawa-Singer M, Stewart AL. Defining novel health-related quality of life domains in lung transplantation: a qualitative analysis. Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation. Jun 2015;24(6):1521-33. doi:10.1007/s11136-014-0875-5

Singer JP, Katz PP, Soong A, et al. Effect of Lung Transplantation on Health-Related Quality of Life in the Era of the Lung Allocation Score: A U.S. Prospective Cohort Study. Am J Transplant. May 2017;17(5):1334-1345. doi:10.1111/ajt.14081

Kolaitis NA, Singer JP. Defining Success in Lung Transplantation: From Survival to Quality of Life. Seminars in respiratory and critical care medicine. Apr 2018;39(2):255-268. doi:10.1055/s-0037-1615801

DeBolt CL, Gao Y, Sutter N, et al. The association of post-operative delirium with patient-reported outcomes and mortality after lung transplantation. Clinical transplantation. Mar 7 2021:e14275. doi:10.1111/ctr.14275

Kolaitis NA, Gao Y, Soong A, et al. Primary graft dysfunction attenuates improvements in health-related quality of life after lung transplantation, but not disability or depression. Am J Transplant. Feb 2021;21(2):815-824. doi:10.1111/ajt.16257

Kolaitis NA, Gao Y, Soong A, et al. Depressive symptoms in lung transplant recipients: trajectory and association with mortality and allograft dysfunction. Thorax. Mar 30 2022;doi:10.1136/thoraxjnl-2021-217612

Perez AA, Singer JP. Patient-Centered Outcomes in Lung Transplantation. Encyclopedia of Respiratory Medicine: Elsevier; 2022. p. 778-786.

Koons B, Aryal S, Blumenthal N, et al. Mismatch identified in symptom burden profiles in lung transplantation. Heart Lung. May-Jun 2023;59:165-172. doi:10.1016/j.hrtlng.2023.02.011

Survey and Frailty Measure Development:

Singer JP, Christie JD, Diamond JM, et al. Development of the Lung Transplant Frailty Scale (LT-FS). The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation. Feb 20 2023;doi:10.1016/j.healun.2023.02.006

Singer JP, Blanc PD, Dean YM, et al. Development and validation of a lung transplant-specific disability questionnaire. Thorax. May 2014;69(5):445-50. doi:10.1136/thoraxjnl-2013-204557

Baldwin MR, Singer JP, Huang D, et al. Refining Low Physical Activity Measurement Improves Frailty Assessment in Advanced Lung Disease and Survivors of Critical Illness. Ann Am Thorac Soc. Apr 11 2017;doi:10.1513/AnnalsATS.201612-1008OC

Singer JP, Soong A, Chen J, et al. Development and Preliminary Validation of the Lung Transplant Quality of Life (LT-QOL) Survey. Am J Respir Crit Care Med. Oct 10 2018;doi:10.1164/rccm.201806-1198OC