What is the PROMISE study?
The study Prospective Multicenter Research on Donor and Recipient Management Strategies to Improve Lung Transplant Outcomes, called PROMISE for short, is led by Dr. Jonathan Singer at the UCSF Lung Transplant Program. The purpose of this study is to find out how to improve the results of lung transplant. To do this, we will collect data, blood samples, and patient-reported outcomes from lung transplant candidates and recipients and the recipient’s lung donor. Ultimately, this may help researchers learn what leads to certain problems and conditions after lung transplantation, including early severe lung injury, when the immune system attacks the newly transplanted lung, infection, and other problems that cause the lung to function poorly. Additionally, we would like to understand how these issues affect your quality of life and survival.
Who can participate?
To participate in the study, you must:
- Be in evaluation for a lung transplant at UCSF
- If you have received a lung transplant at UCSF within the previous 30 days, you are still able to enroll in the study
Be ≥ 18 years of age
What is asked of participants?
We will collect information known as clinical data from your electronic medical record, blood samples, and questionnaires (patient-reported outcomes) that give researchers information about how you are doing and feeling. We will collect information and samples in person, through phone calls, mail, text, online surveys, or other ways. We will do our best to collect blood samples for research during your routine lab visits. But if you do not have a scheduled routine blood draw, we may ask you to have blood drawn for research only. If additional samples are needed, researchers will contact you for your permission, and coordinate with your care team to collect them while you are already receiving normal medical care.
How do I sign up?
The PROMISE study is currently enrolling. If you are interested in participating, please reach out to research coordinators Cassie Cruz ([email protected]) or Paige Gambetta ([email protected]) to learn more.